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COPPER, SERUM/PLASMA
Number 82
CPT Code 82525
Alias COPPER, SERUM/PLASMA
Specimen Container Royal Blue Top
Specimen Type Plasma
Turn Around Time
Days Performed
Reference Range 72-166 ug/dL
Alternate Specimen Royal Blue Top Serum
Volume 1 mL Plasma
Stability Ambient 14 Days
Stability Refrigerated 14 Days
Stability Frozen 14 Days
Patient Preparation
Methodology
Inductively coupled plasma/mass spectrometry (ICP/MS)
Limitations
Serum ceruloplasmin is an acute-phase reactant type protein, and since it binds a large portion of serum copper, both serum copper and ceruloplasmin increase under the influence of inflammatory conditions and estrogen. Serum copper is, therefore, elevated in pregnancy, in patients on estrogens and estrogen-containing contraceptive drugs, in rheumatoid arthritis, and a number of pathologic entities. It may be low with low serum proteins as in nephrosis, malabsorption, and malnutrition without necessarily reflecting inadequate liver copper stores.
Rejection Criteria
Additional Instructions
Performing Laboratory Reference Laboratory
TagsCU, METAL