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ANTI HISTONE ANTIBODY
Number 397
CPT Code 86235
Alias HISTONE ANTIBODIES
Specimen Container SST
Specimen Type Serum
Turn Around Time
Days Performed
Reference Range Negative: <1.0 units
Alternate Specimen Red Top
Volume 1 mL Serum
Stability Ambient 14 Days
Stability Refrigerated 14 Days
Stability Frozen 14 Days
Patient Preparation
Methodology
Enzyme-linked immunoabsorbent assay (ELISA)
Limitations
The expected value in the normal population is negative; however, apparently healthy individuals may contain ANA in their sera. This percentage increases with aging, particularly in the seventh decade of life. Certain therapeutic drug regimens and viral syndromes may also cause ANAs.
Rejection Criteria
Hemolysis; icterus; lipemia; bacterial contamination
Additional Instructions
Performing Laboratory Reference Laboratory
TagsANTIHISTONE, DIL, DRUG INDUCED LUPUS, H2A/H2B, H3, H4