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PLASMINOGEN ACTIVITY
Number 657
CPT Code 85420
Alias
Specimen Container Blue Top Citrate
Specimen Type Plasma Citrate
Turn Around Time
Days Performed
Reference Range Contact Laboratory
Alternate Specimen
Volume 2 mL Plasma
Stability Ambient Unstable
Stability Refrigerated Unstable
Stability Frozen Preferred
Patient Preparation
Ideally, the patient should not be on anticoagulant therapy. Avoid warfarin (Coumadin®) therapy for two weeks prior to the test and heparin, direct Xa, and thrombin inhibitor therapies for about three days prior to testing.
Methodology
Streptokinase (SK) as mixed with the patient sample and the resulting plasminogen-SK complex converts a chromogenic substrate to produce color.
Limitations
Plasminogen levels can be decreased in disseminated intravascular coagulation (DIC), hepatitis, leukemia, and with thrombolytic therapy.
Rejection Criteria
Severe hemolysis; improper labeling; clotted specimen; specimen diluted with IV fluids; samples thawed in transit; improper sample type; sample out of stability
Additional Instructions
Performing Laboratory Reference Laboratory
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