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ACTIVATED PROTEIN C RESISTANCE
Number 985
CPT Code 85307
Alias PROTEIN C RESISTANCE
Specimen Container Blue Top Citrate
Specimen Type Plasma Citrate
Turn Around Time
Days Performed
Reference Range 2.0-4.0 Ratio
Alternate Specimen
Volume 2 mL Plasma
Stability Ambient
Stability Refrigerated
Stability Frozen
Patient Preparation
DO NOT DRAW FROM AN ARM WITH A HEPARIN LOCK OR HEPARINIZED CATHETER. IDEALLY, PATIENT SHOULD NOT BE ON ANTICOAGULANT THERAPY. AVOID WARFARIN (COUMADIN) THERAPY FOR TWO WEEKS AND HEPARIN THREE DAYS PRIOR TO TESTING.
Methodology
Effects of adding aPC on the activated partial thromboplastin time of patient’s sample
Limitations
This assay detects thrombotic risk factors other than factor V Leiden. This test should not be performed on individuals with extended baseline aPTT values due to the presence of lupus anticoagulants. This test should not be used for patients receiving thrombin inhibitors such as hirudin and argatroban.
Rejection Criteria
Gross hemolysis, clotted specimen tubes <90% full
Additional Instructions
Performing Laboratory Reference Laboratory
TagsAPCR