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ACCUTYPE IL28B
Number 1342
CPT Code 81400
Alias INTERLEUKIN 28B POLYMORPHISM, ACCUTYPE
Specimen Container Lavender Top
Specimen Type Whole Blood EDTA
Turn Around Time
Days Performed
Reference Range
Alternate Specimen Two buccal swabs
Volume 7 mL Whole Blood
Stability Ambient
Stability Refrigerated
Stability Frozen
Patient Preparation
Methodology
Real-Time PCR with allele specific TaqMan probes
Limitations
IL28B genotype is only one of many factors that can influence response rates to pegylated interferon/ribavirin therapy in HCV genotype 1 infection and should be interpreted in the context of other clinical factors. The mechanism by which the IL28B genotype mediates pegylated interferon/ribavirin treatment response in HCV genotype 1 is not yet understood and is the subject of intense research. The impact of the IL28B polymorphism on response rates in HCV genotypes other than genotype 1 is still being investigated.
Rejection Criteria
Frozen specimen, hemolysis, improper container, 1 buccal swab, wet buccal swab
Additional Instructions
Performing Laboratory Reference Laboratory
TagsHCV, IL28, IL28B, INTERLEUKIN 28B, RS12979860